High glucose inhibits glucose‐6‐phosphate dehydrogenase, leading to increased oxidative stress and β‐cell apoptosis-Reference-Cited by-同舟云学术

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High glucose inhibits glucose‐6‐phosphate dehydrogenase, leading to increased oxidative stress and β‐cell apoptosis

Published:2009-12-23 Issue:5 Volume:24 Page:1497-1505
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Zhang Zhaoyun¹,Liew Chong Wee¹,Handy Diane E.²,Zhang Yingyi²,Leopold Jane A.²,Hu Ji¹,Guo Lili¹,Kulkarni Rohit N.¹,Loscalzo Joseph²,Stanton Robert C.¹

Affiliation:

1. Research DivisionJoslin Diabetes CenterHarvard Medical SchoolBostonMassachusettsUSA

2. Cardiovascular DivisionDepartment of MedicineBrigham and Women's HospitalHarvard Medical SchoolBostonMassachusettsUSA

Funder

National Institutes of Health

National Institute of Diabetes and Digestive and Kidney Diseases

National Heart, Lung, and Blood Institute

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.09-136572

Reference50 articles.

1. Oxidative stress: the vulnerable β-cell

2. Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues

3. Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells

4. β-Cell Failure in Diabetes and Preservation by Clinical Treatment

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