Regulation of astrocyte inflammatory responses by the Parkinson's disease‐associated gene DJ

Regulation of astrocyte inflammatory responses by the Parkinson's disease‐associated gene DJ–1

Published:2009-03-10 Issue:8 Volume:23 Page:2478-2489
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Waak Jens¹,Weber Stephanie S.¹,Waldenmaier Andrea²,Görner Karin²,Alunni‐Fabbroni Marianna²,Schell Heinrich¹,Vogt‐Weisenhorn Daniela³,Pham Thu‐Trang³,Reumers Veerle⁴,Baekelandt Veerle⁴,Wurst Wolfgang³,Kahle Philipp J.¹

Affiliation:

1. Laboratory of Functional NeurogeneticsDepartment of NeurodegenerationHertie Institute for Clinical Brain ResearchTübingenGermany

2. Olympus Life Science Research Europe BBD Advalytix ProductsMunichGermany

3. Helmholtz Center MunichInstitute of Developmental GeneticsNeuherbergGermany

4. Laboratory for Neurobiology and Gene TherapyDivision of Molecular MedicineDepartment of Molecular and Cellular MedicineKatholieke Universiteit LeuvenLeuvenBelgium

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.08-125153

Reference45 articles.

1. Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism

2. The role of pathogenicDJ-1 mutations in Parkinson's disease

3. Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization

4. Differential Effects of Parkinson's Disease-associated Mutations on Stability and Folding of DJ-1

5. A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization

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