Acetaminophen,viaits reactive metaboliteN-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents

Author:

Nassini Romina1,Materazzi Serena1,Andrè Eunice1,Sartiani Laura1,Aldini Giancarlo2,Trevisani Marcello3,Carnini Chiara4,Massi Daniela5,Pedretti Pamela1,Carini Marina2,Cerbai Elisabetta1,Preti Delia6,Villetti Gino4,Civelli Maurizio4,Trevisan Gabriela1,Azzari Chiara7,Stokesberry Susan8,Sadofsky Laura9,McGarvey Lorcan8,Patacchini Riccardo4,Geppetti Pierangelo1

Affiliation:

1. Department of Preclinical and Clinical Pharmacology,

2. Department of Pharmaceutical Sciences, University of Milan, Milan, Italy;

3. Pharmeste Srl, Ferrara, Italy;

4. Pharmacology Department, Chiesi Farmaceutici SpA, Parma, Italy;

5. Department of Human Pathology and Oncology, and

6. Department of Pharmaceutical Chemistry, University of Ferrara, Ferrara, Italy;

7. Department of Pediatrics, University of Florence, Florence, Italy;

8. Centre for Infection and Immunity, Queen's University Belfast, Belfast, UK; and

9. Division of Cardiovascular and Respiratory Studies, University of Hull, Castle Hill Hospital, Hull, UK

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

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