Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA‐2, IA‐2β, and GAD65-Reference-Cited by-同舟云学术

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Multiple microRNAs within the 14q32 cluster target the mRNAs of major type 1 diabetes autoantigens IA‐2, IA‐2β, and GAD65

Published:2015-07-06 Issue:10 Volume:29 Page:4374-4383
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Abuhatzira Liron¹,Xu Huanyu¹,Tahhan Georges¹,Boulougoura Afroditi¹,Schäffer Alejandro A.²,Notkins Abner L.¹

Affiliation:

1. Experimental Medicine Section, Laboratory of Sensory BiologyNational Institute of Dental and Craniofacial ResearchBethesdaMarylandUSA

2. National Center for Biotechnology Information, National Library of Medicine, National Institutes of HealthBethesdaMarylandUSA

Funder

National Institute of Dental and Craniofacial Research

U.S. National Library of Medicine

National Institutes of Health

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.15-273649

Reference47 articles.

1. Autoantibodies in Diabetes

2. Deletion of Ia-2 and/or Ia-2β in mice decreases insulin secretion by reducing the number of dense core vesicles

3. Overexpression of the autoantigen IA-2 puts beta cells into a pre-apoptotic state: autoantigen-induced, but non-autoimmune-mediated, tissue destruction

4. The Neurosecretory Vesicle Protein Phogrin Functions as a Phosphatidylinositol Phosphatase to Regulate Insulin Secretion

5. Dense Core Vesicle Proteins IA-2 and IA-2β

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1. A set of circulating microRNAs belonging to the 14q32 chromosome locus identifies two subgroups of individuals with recent-onset type 1 diabetes;Cell Reports Medicine;2024-06

2. A set of circulating microRNAs belonging to the 14q32 chromosomic locus identifies two clinically and phenotypically different subgroups of individuals with recent onset Stage 3 type 1 diabetes;2023-10-09

3. Altered Expression of Vitamin D Metabolism Genes and Circulating MicroRNAs in PBMCs of Patients with Type 1 Diabetes: Their Association with Vitamin D Status and Ongoing Islet Autoimmunity;Non-Coding RNA;2023-10-07

4. Biology and Natural History of Type 1 Diabetes Mellitus;Current Pediatric Reviews;2023-08

5. Hereditable variants of classical protein tyrosine phosphatase genes: Will they prove innocent or guilty?;Frontiers in Cell and Developmental Biology;2023-01-23

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