Oxidative stress‐induced activation of Lyn recruits sphingomyelinase and is requisite for its stimulation by Ara‐C

Author:

Bezombes Christine1,Plo Isabelle1,Mas Véronique Mansat-De2,Quillet-Mary Anne1,Nègre-Salvayre Anne3,Laurent Guy12,Jaffrézou Jean-Pierre1

Affiliation:

1. INSERM E9910Institut Claudius Régaud 20 rue du Pont St Pierre Toulouse 31052 France

2. Service d'HématologieCentre Hospitalier Universitaire Purpan Toulouse 31059 France

3. Laboratoire de Biochimie MédicaleINSERM 466Centre Hospitalier Universitaire Rangueil Toulouse 31403 France

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference31 articles.

1. Dose schedule and antitumor studies of arabinoyl cytosine;Frei E.;Cancer Res.,1969

2. DNA strand breaks caused by inhibitors of DNA synthesis: 1-β-D-arabinofuranosylcytosine and aphidicolin;Fram R. J.;Cancer Res.,1982

3. Induction of internucleosomal DNA fragmentation in human myeloid leukemia cells by 1-β-D-arabinofuranosylcytosine;Gunji H.;Cancer Res.,1991

4. Functions of Ceramide in Coordinating Cellular Responses to Stress

5. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis

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