<scp>AKT1</scp> phosphorylates <scp>RBM17</scp> to promote Sox2 transcription by modulating alternative splicing of <scp>FOXM1</scp> to enhance cancer stem cell properties in colorectal cancer cells-Reference-Cited by-同舟云学术

AKT1 phosphorylates RBM17 to promote Sox2 transcription by modulating alternative splicing of FOXM1 to enhance cancer stem cell properties in colorectal cancer cells

Published:2022-12-15 Issue:1 Volume:37 Page:
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:The FASEB Journal

Author:

Fu Yan¹²³⁴,Bai Chen²,Wang Shengsheng²,Chen Denggang²,Zhang Peng²,Wei Hailang²,Rong Fan³,Zhang Chao⁴,Chen Shaojuan⁵,Wang Zhenjun¹^ORCID

Affiliation:

1. Department of General Surgery Beijing Chao‐Yang Hospital, Capital Medical University Beijing People's Republic of China

2. Department of General Surgery Taihe Hospital, Hubei University of Medicine Shiyan China

3. Hubei Key Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine Shiyan China

4. Center for Evidence Based Medicine and Clinical Research, Taihe Hospital, Hubei University of Medicine Shiyan China

5. Department of Stomatology Taihe Hospital, Hubei University of Medicine Shiyan China

Funder

Hubei University of Medicine

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.202201255R

Reference31 articles.

1. Epidemiology and risk factors of colorectal cancer in China

2. Molecular Targeted Drugs and Treatment of Colorectal Cancer: Recent Progress and Future Perspectives

3. Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment

4. Alternative splicing as a regulator of development and tissue identity

5. Roles and mechanisms of alternative splicing in cancer — implications for care

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