Augmentation of cardiac contractility with no change in L‐type Ca 2+ current in transgenic mice with a cardiac‐directed expression of the human adenylyl cyclase type 8 (AC8)

Author:

Georget Marie1,Mateo Philippe1,Vandecasteele Grégoire1,Jurevičius Jonas12,Lipskaia Larissa3,Defer Nicole3,Hanoune Jacques3,Hoerter Jacqueline1,Fischmeister Rodolphe1

Affiliation:

1. Laboratoire de Cardiologie Cellulaire et Moléculaire, INSERM U‐446Université Paris‐Sud, Faculté de Pharmacie F‐92296 Châtenay‐Malabry France

2. Laboratory of Membrane Biophysics, Institute of CardiologyKaunas University of Medicine 3007 Kaunas Lithuania

3. Laboratoire de Régulation des Gènes et Signalisation Cellulaire, INSERM U‐99Hôpital Henri‐Mondor F‐94010 Créteil France

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference43 articles.

1. Functional Analysis of Myocardial Performance in Murine Hearts Overexpressing the Humanβ2-Adrenergic Receptor

2. Type VIII adenylyl cyclase;Cali J. J.;A Ca2+/calmodulin‐stimulated enzyme expressed in discrete regions of rat brain. J. Biol. Chem,1994

3. Overexpression of the Cardiac β 2 -Adrenergic Receptor and Expression of a β-Adrenergic Receptor Kinase-1 (βARK1) Inhibitor Both Increase Myocardial Contractility but Have Differential Effects on Susceptibility to Ischemic Injury

4. Tissue specificity and physiological relevance of various isoforme of adenylyl cyclase;Defer N.;Am. J. Physiol,2000

5. Molecular cloning of the human type VIII adenylyl cyclase

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