SirT1 catalytic activity is required for male fertility and metabolic homeostasis in mice-Reference-Cited by-同舟云学术

SirT1 catalytic activity is required for male fertility and metabolic homeostasis in mice

Published:2011-10-17 Issue:2 Volume:26 Page:555-566
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Seifert Erin L.¹²,Caron Annabelle Z.¹²,Morin Katy¹²³,Coulombe Josée¹²,He Xiao Hong¹²,Jardine Karen²,Dewar‐Darch Danielle¹²,Boekelheide Kim⁴,Harper Mary‐Ellen³,McBurney Michael W.¹²³

Affiliation:

1. Program for Cancer TherapeuticsOttawa Hospital Research Institute OtttawaOntario Canada

2. Department of Medicine, Microbiology, and ImmunologyUniversity of Ottawa OttawaOntario Canada

3. Department of Biochemistry, Microbiology, and ImmunologyUniversity of Ottawa OttawaOntario Canada

4. Department of Pathology and Laboratory MedicineWarren Alpert Medical School of Brown University School of Medicine ProvidenceRhode Island USA

Funder

Canadian Institutes of Health Research

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.11-193979

Reference54 articles.

1. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

2. The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

3. A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family

4. An Enzymatic Activity in the Yeast Sir2 Protein that Is Essential for Gene Silencing

5. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

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