Depleting interferon regulatory factor‐1(IRF‐1) with CRISPR/Cas9 attenuates inducible oxidative metabolism without affecting RA‐induced differentiation in HL‐60 human AML cells
Author:
Affiliation:
1. Department of Biomedical Sciences Cornell University Ithaca NY USA
2. City University of Hong Kong ShenZhen Research Institute ShenZhen China
3. Department of Biomedical Sciences City University of Hong Kong Hong Kong China
Funder
National Institutes of Health
National Natural Science Foundation of China
Publisher
Wiley
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1096/fba.2020-00004
Reference48 articles.
1. Retinoic acid (RA) and As2O3 treatment in transgenic models of acute promyelocytic leukemia (APL) unravel the distinct nature of the leukemogenic process induced by the PML-RARalpha and PLZF-RARalpha oncoproteins
2. HL-60 cell line was derived from a patient with FAB-M2 and not FAB-M3
3. Retinoic Acid Therapy Resistance Progresses from Unilineage to Bilineage in HL-60 Leukemic Blasts
4. 1,25-dihydroxyvitamin D3 inhibits proliferation of human promyelocytic leukaemia (HL60) cells and induces monocyte-macrophage differentiation in HL60 and normal human bone marrow cells
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1. Vacuolin-1 enhances RA-induced differentiation of human myeloblastic leukemia cells: evidence for involvement of a CD11b/FAK/LYN/SLP-76 axis subject to endosomal regulation that drives late differentiation steps;Cell & Bioscience;2022-11-03
2. The high-performance technology CRISPR/Cas9 improves knowledge and management of acute myeloid leukemia;Biomedical Papers;2021-09-20
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