Characterization and computational simulation of human Syx, a RhoGEF implicated in glioblastoma-Reference-Cited by-同舟云学术

Characterization and computational simulation of human Syx, a RhoGEF implicated in glioblastoma

Published:2022-05-31 Issue:7 Volume:36 Page:
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:The FASEB Journal

Author:

Boyd Ryan J.¹^ORCID,Olson Tien L.¹,Zook James D.¹,Stein Derek¹,Aceves Manuel¹,Lin Wan‐Hsin²,Craciunescu Felicia M.¹,Hansen Debra T.¹³,Anastasiadis Panos Z.²,Singharoy Abhishek¹,Fromme Petra¹^ORCID

Affiliation:

1. Biodesign Center for Applied Structural Discovery Arizona State University Tempe Arizona USA

2. Department of Cancer Biology Mayo Clinic Jacksonville Florida USA

3. Center for Innovations in Medicine Arizona State University Tempe Arizona USA

Funder

National Institutes of Health

Center for Clinical and Translational Science, Mayo Clinic

Biodesign Institute, Arizona State University

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.202101808RR

Reference81 articles.

1. K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions

2. The Evolutionary Landscape of Dbl-Like RhoGEF Families: Adapting Eukaryotic Cells to Environmental Signals

3. Structural basis for the selective activation of Rho GTPases by Dbl exchange factors

4. ROCK and Dia have opposing effects on adherens junctions downstream of Rho

5. Regulation of Small GTPases by GEFs, GAPs, and GDIs

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