Cf‐02, a novel benzamide‐linked small molecule, blunts NF‐κB activation and NLRP3 inflammasome assembly and improves acute onset of accelerated and severe lupus nephritis in mice

Author:

Yang Shin‐Ruen12,Hua Kuo‐Feng34,Yang Chih‐Yu56,Chen Ann2ORCID,Weng Jui‐Chun7,Tsai Yu‐Ling2,Wan Chih‐Jun1,Wu Chung‐Yao2,Lee Chia‐Chung8,Chan Jia‐Feng9,Hsieh Chih‐Yu910,Hsu Yu‐Juei11,Wu Chia‐Chao11,Mukhopadhyay Debabrata12,Huang Hsu‐Shan813ORCID,Liu Feng‐Cheng14ORCID,Ka Shuk‐Man7ORCID

Affiliation:

1. Department of Medicine Graduate Institute of Aerospace and Undersea Medicine Academy of MedicineNational Defense Medical Center Taipei Taiwan

2. Department of Pathology Tri‐Service General Hospital, National Defense Medical Center Taipei Taiwan

3. Department of Biotechnology and Animal Science National Ilan University Ilan Taiwan

4. Department of Medical Research China Medical University HospitalChina Medical University Taichung Taiwan

5. Institute of Clinical Medicine School of Medicine National Yang Ming Chiao Tung University Taipei Taiwan

6. Division of Nephrology Department of Medicine Taipei Veterans General Hospital Taipei Taiwan

7. Graduate Institute of Life Sciences National Defense Medical Center Taipei Taiwan

8. Graduate Institute of Cancer Biology and Drug Discovery College of Medical Science and Technology Taipei Medical University Taipei Taiwan

9. Division of Nephrology Department of Internal Medicine En Chu Kong Hospital New Taipei City Taiwan

10. College of Biomedical Engineering Taipei Medical University Taipei Taiwan

11. Division of Nephrology Department of Medicine Tri‐Service General Hospital, National Defense Medical Center Taipei Taiwan

12. Department of Biochemistry and Molecular Biology Mayo Clinic Rochester MN USA

13. Graduate Institute of Medical Sciences National Defense Medical Center Taipei Taiwan

14. Department of Rheumatology/Immunology and Allergy Department of Medicine Tri‐Service General Hospital, National Defense Medical Center Taipei Taiwan

Funder

Tri-Service General Hospital

Ministry of Science and Technology

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

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