p97 dysfunction underlies a loss of quality control of damaged membrane proteins and promotes oxidative stress and sickling in sickle cell disease

Author:

Song Anren1,Wen Alexander Q.12,Wen Y. Edward13,Dzieciatkowska Monika4ORCID,Kellems Rodney E.15,Juneja Harinder S.6,D'Alessandro Angelo4,Xia Yang15ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology the University of Texas McGovern Medical School Houston Texas USA

2. University of California at San Diego La Jolla California USA

3. University of Texas Southwestern Medical School Dallas Texas USA

4. Department of Biochemistry and Molecular Genetics University of Colorado School of Medicine Aurora Colorado USA

5. Graduate Program in Biochemistry and Cell Biology University of Texas MD Anderson UTHealth Graduate School of Biomedical Sciences Houston Texas USA

6. Department of Internal Medicine Divison of Hematology the University of Texas McGovern Medical School Houston Texas USA

Funder

American Heart Association

McGovern Medical School

National Institutes of Health

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference57 articles.

1. Population Estimates of Sickle Cell Disease in the U.S.

2. Sickle cell disease

3. Pathophysiology of Sickle Cell Disease

4. Metabolomic and molecular insights into sickle cell disease and innovative therapies

5. Peculiar elongated and sickle‐shaped red blood corpuscles in a case of severe anemia. 1910;Herrick JB;Yale J Biol Med,2001

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