SU6668 inhibits Flk‐1/KDR and PDGFRβ in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice-Reference-Cited by-同舟云学术

SU6668 inhibits Flk‐1/KDR and PDGFRβ in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice

Published:2002-05 Issue:7 Volume:16 Page:681-690
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Laird A. Douglas¹,Christensen James G.¹,Li Guangmin¹,Carver Jeremy¹,Smith Kimberly¹,Xin Xiaohua¹,Moss Katherine G.¹,Louie Sharianne G.¹,Mendel Dirk B.¹,Cherrington Julie M.¹

Affiliation:

1. SUGEN, Inc., Preclinical Research and Translational MedicineSouth San FranciscoCaliforniaUSA

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.01-0700com

Reference23 articles.

1. Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

2. Regulation of Mammalian O2 Homeostasis by Hypoxia-Inducible Factor 1

3. Matrix Metalloproteinases: Biologic Activity and Clinical Implications

4. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, Angiopoietins, and ephrins in vascular development

5. New paradigms for the treatment of cancer: The role of anti-angiogenesis agents

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