1. Department of Biochemistry, Juntendo University School of Medicine, Tokyo, Japan;
2. Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children’s Hospital, Boston, Massachusetts, USA;
3. Department of Anesthesia, Harvard Medical School, Boston, Massachusetts, USA;
4. Department of Anesthesia and Critical Care, University of Pennsylvania, Philadelphia, Pennsylvania, USA;
5. Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan