Liquid‐liquid phase separation and fibrillation of the prion protein modulated by a high‐affinity DNA aptamer

Author:

Matos Carolina O.1,Passos Yulli M.2,Amaral Mariana J.3,Macedo Bruno2,Tempone Matheus H.2,Bezerra Ohanna C. L.4,Moraes Milton O.4,Almeida Marcius S.3,Weber Gerald5,Missailidis Sotiris6,Silva Jerson L.3,Uversky Vladimir N.78,Pinheiro Anderson S.1,Cordeiro Yraima2

Affiliation:

1. Department of Biochemistry Institute of Chemistry Federal University of Rio de Janeiro Rio de Janeiro Brazil

2. Faculty of Pharmacy Federal University of Rio de Janeiro Rio de Janeiro Brazil

3. Institute of Medical Biochemistry Leopoldo de Meis National Center for Structural Biology and Bioimaging (CENABIO) Federal University of Rio de Janeiro Rio de Janeiro Brazil

4. Leprosy Laboratory Oswaldo Cruz Institute Oswaldo Cruz Foundation (FIOCRUZ) Rio de Janeiro Brazil

5. Department of Physics Federal University of Minas Gerais Belo Horizonte Brazil

6. Institute of Technology in Immunobiologics (Bio‐Manguinhos) Oswaldo Cruz Foundation (FIOCRUZ) Rio de Janeiro Brazil

7. Department of Molecular Medicine USF Health Byrd Alzheimer's Research Institute Morsani College of Medicine University of South Florida Tampa FL USA

8. Laboratory of New Methods in Biology Institute for Biological Instrumentation Russian Academy of Sciences Pushchino Russia

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

Brown University

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

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