HMG‐CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage
Author:
Affiliation:
1. Institute of Environmental MedicineKarolinska Institutet S-17177 Stockholm
2. Neurotec DepartmentDivision of Geriatric MedicineKarolinska InstitutetKarolinska University Hospital Huddinge Stockholm Sweden
Publisher
Wiley
Subject
Genetics,Molecular Biology,Biochemistry,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.04-2745fje
Reference43 articles.
1. Regulation of the mevalonate pathway
2. Safety of statins: Focus on clinical pharmacokinetics and drug interactions;Bellosta S.;Circulation,2004
3. The statins as anticancer agents;Chan K. K.;Clin. Cancer Res.,2003
4. Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma. A randomized controlled trial
5. Statin use and cancer risk in the General Practice Research Database
Cited by 47 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Functional significance of cholesterol metabolism in cancer: from threat to treatment;Experimental & Molecular Medicine;2023-09-01
2. Targeting of Mevalonate-Isoprenoid Pathway in Acute Myeloid Leukemia Cells by Bisphosphonate Drugs;Biomedicines;2022-05-16
3. Effects of octacosanol on HMG-CoA reductase and cyclooxygenase-2 activities in the HT-29 human colorectal cancer cell line;ScienceAsia;2022
4. Cholesterol-Lowering Drugs on Akt Signaling for Prevention of Tumorigenesis;Frontiers in Genetics;2021-09-16
5. LDLR inhibition promotes hepatocellular carcinoma proliferation and metastasis by elevating intracellular cholesterol synthesis through the MEK/ERK signaling pathway;Molecular Metabolism;2021-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3