Transgenic expression of a dominant negative KATPchannel subunit in the mouse endothelium: effects on coronary flow and endothelin‐1 secretion

Author:

Malester Brian12,Tong XiaoYong3,Ghiu Ioana4,Kontogeorgis Andrianos5,Gutstein David E.5,Xu Jie1,Hendricks-Munoz Karen D.1,Coetzee William A.162

Affiliation:

1. Department of PediatricsNYU School of MedicineNew YorkNew YorkUSA

2. Department of Physiology and NeuroscienceNYU School of MedicineNew YorkNew YorkUSA

3. Department of MedicineBoston University School of MedicineBostonMassachusettsUSA

4. American Cardiovascular Research InstituteAtlantaGeorgiaUSA

5. Department of MedicineNYU School of MedicineNew YorkNew YorkUSA

6. Department of PharmacologyNYU School of MedicineNew YorkNew YorkUSA

Funder

National Institutes of Health

American Heart Association

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference55 articles.

1. Functional Roles Of KATP Channels In Vascular Smooth Muscle

2. KATP channels and basal coronary vascular tone

3. Adenosine potentiates flow-induced dilation of coronary arterioles by activating KATP channels in endothelium;Kuo L.;Am. J. Physiol.,1995

4. Endothelial ATP-sensitive potassium channels mediate coronary microvascular dilation to hyperosmolarity;Ishizaka H.;Am. J. Physiol.,1997

5. Heterogeneous populations of K+ channels mediate EDRF release to flow but not agonists in rabbit aorta;Hutcheson I. R.;Am. J. Physiol.,1994

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