T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy

Author:

Alessandri Cristiano1,Barbati Cristiana23,Vacirca Davide2,Piscopo Paola2,Confaloni Annamaria2,Sanchez Massimo2,Maselli Angela2,Colasanti Tania23,Conti Fabrizio1,Truglia Simona1,Perl Andras4,Valesini Guido1,Malorni Walter536,Ortona Elena2,Pierdominici Marina2

Affiliation:

1. Lupus Clinic, Dipartimento di Medicina Interna e Specialità MedicheSapienza UniversityRomeItaly

2. Department of Cell Biology and NeurosciencesIstituto Superiore di SanitàRomeItaly

3. San Raffaele Institute SulmonaL'AquilaItaly

4. Division of Rheumatology, Department of MedicineState University of New YorkSyracuseNew YorkUSA

5. Department of Therapeutic Research and Medicine EvaluationIstituto Superiore di SanitàRomeItaly

6. Center of Integrated MetabolomicsRomeItaly

Funder

Ministero della Salute

National Institutes of Health

Alliance for Lupus Research

Central New York Community Foundation

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference60 articles.

1. Pathogenesis of human systemic lupus erythematosus: recent advances

2. mTOR signaling: a central pathway to pathogenesis in systemic lupus erythematosus?;Fernandez D.;Discov. Med.,2010

3. Abnormalities of T cell signaling in systemic lupus erythematosus;Moulton V. R.;Arthritis Res. Ther.,2011

4. Life and death in peripheral T cells

5. Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus;Emlen W.;J. Immunol.,1994

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