Glucose and leptin induce apoptosis in human β‐ cells and impair glucose‐stimulated insulin secretion through activation of c‐Jun N‐terminal kinases-Reference-Cited by-同舟云学术

Glucose and leptin induce apoptosis in human β‐ cells and impair glucose‐stimulated insulin secretion through activation of c‐Jun N‐terminal kinases

Published:2008-02-08 Issue:6 Volume:22 Page:1905-1913
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Maedler Kathrin¹,Schulthess Fabienne T.¹,Bielman Christelle²,Berney Thierry³,Bonny Christophe²,Prentki Marc⁴,Donath Marc Y.⁵,Roduit Raphael²⁶

Affiliation:

1. Larry L. Hillblom Islet Research CenterUniversity of CaliforniaLos AngelesCaliforniaUSA

2. Medical Genetic ServiceCentre Hospitalier Universitarie Vaudois LausanneLausanneFrance

3. Department of SurgeryUniversity Medical CenterGenevaSwitzerland

4. Molecular Nutrition Unit and the Montreal Diabetes Research CenterCentre de Recherche du CHUM, and Department of Nutrition and BiochemistryUniversite de MontréalMontréalQuebecCanada

5. Division of Endocrinology and DiabetesUniversity Hospital ZurichUniversity of ZurichSwitzerland

6. Institut de Recherche en OphtalmologieSionSwitzerland

Funder

Larry L. Hillblom Foundation

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.07-101824

Reference68 articles.

1. Islet cell failure in type 2 diabetes

2. β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

3. Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications

4. Mechanisms of β‐cell death in type 2 diabetes;Donath M. Y.;Diabetes,2005

5. Type 2 Diabetes-a Matter of ß-Cell Life and Death?

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