ATM inhibitor KU‐55933 induces apoptosis and inhibits motility by blocking GLUT1‐mediated glucose uptake in aggressive cancer cells with sustained activation of Akt-Reference-Cited by-同舟云学术

ATM inhibitor KU‐55933 induces apoptosis and inhibits motility by blocking GLUT1‐mediated glucose uptake in aggressive cancer cells with sustained activation of Akt

Published:2021-03-14 Issue:4 Volume:35 Page:
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Harris Benjamin R. E.¹,Zhang Ye¹²,Tao Jianxin¹³,Shen Renhui¹³,Zhao Xiaoqian³,Cleary Margot P.¹⁴,Wang Tong²³,Yang Da‐Qing¹⁴

Affiliation:

1. The Hormel Institute University of Minnesota Austin MN USA

2. Wuxi People's Hospital Wuxi People's Republic of China

3. Nanjing Medical University Nanjing People's Republic of China

4. The Masonic Cancer Center University of Minnesota Minneapolis MN USA

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.202001415RR

Reference47 articles.

1. The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

2. Fundamentals of cancer metabolism

3. Akt Stimulates Aerobic Glycolysis in Cancer Cells

4. Measuring relative utilization of aerobic glycolysis in breast cancer cells by positional isotopic discrimination

5. Facilitative glucose transporters: Implications for cancer detection, prognosis and treatment

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