Polyphyllin I attenuates cognitive impairments and reduces AD‐like pathology through CIP2A‐PP2A signaling pathway in 3XTg‐AD mice

Author:

Zhou Ying12,Yang Dichen3,Chen Hao3,Zheng Chenfei1,Jiang Huanchang3,Liu Xiaoyuan3,Huang Xingzhou4,Ye Simin3,Song Shuangshuang3,Jiang Nan3,Zhao Zhongyuan3,Ma Shuqing3,Ma Jun5,Huang Kate5,Chen Chaosheng1,Fan Xiaofang6,Gong Yongsheng6,Wang Xiaochuan7,Fan Junming6,Liu Rong7,Shentu Yangping25

Affiliation:

1. Department of Nephrology The First Affiliated Hospital of Wenzhou Medical University Wenzhou China

2. Key Laboratory of Diagnosis and Treatment of Severe Hepato‐Pancreatic Diseases of Zhejiang Province The First Affiliated Hospital of Wenzhou Medical University Wenzhou China

3. Wenzhou Medical University Wenzhou China

4. Central laboratory The First Affiliated Hospital of Wenzhou Medical University Wenzhou China

5. Department of Pathology The First Affiliated Hospital of Wenzhou Medical University Wenzhou China

6. Institute of Hypoxia Medicine School of Basic Medical Sciences Wenzhou Medical University Wenzhou China

7. Department of Pathophysiology Key Laboratory of Ministry of Education for Neurological Disorders School of Basic Medicine Tongji Medical CollegeHuazhong University of Science and Technology Wuhan China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Wenzhou Municipal Science and Technology Bureau

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

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