Tau knockout exacerbates degeneration of parvalbumin‐positive neurons in substantia nigra pars reticulata in Parkinson's disease‐related α‐synuclein A53T mice-Reference-Cited by-同舟云学术

Tau knockout exacerbates degeneration of parvalbumin‐positive neurons in substantia nigra pars reticulata in Parkinson's disease‐related α‐synuclein A53T mice

Published:2020-07-30 Issue:9 Volume:34 Page:12239-12254
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Jiao Luyan¹²,Zheng Meige³,Duan Jinhai⁴,Wu Ting¹²,Li Zhao¹²,Liu Lin¹²,Xiang Xianhong⁵,Tang Xiaolu⁶,He Jinyang⁷,Li Xingjian¹²,Zhang Guofeng¹²,Ding Jinhui⁸,Cai Huaibin⁹,Lin Xian¹²

Affiliation:

1. Guangdong Province Key Laboratory of Brain Function and Disease Zhongshan School of MedicineSun Yat‐sen University Guangzhou China

2. Department of Anatomy Zhongshan School of MedicineSun Yat‐sen University Guangzhou China

3. Department of Orthopaedics The Second Hospital of Anhui Medical University Hefei China

4. Guangdong Institute of Geriatrics. Department of Neurology Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guanzhou China

5. Department of Interventional Radiology The First Affiliated Hospital of Sun Yat‐Sen University Guangzhou China

6. Department of Human Anatomy College of Basic Medicine Gannan Medical University, University Park of Rongjiang New District Ganzhou China

7. Tropical medicine Institute Guangzhou University of Chinese Medicine Guangzhou China

8. Bioinformatics Core Laboratory of Neurogenetics National Institute on AgingNational Institutes of Health Bethesda MD USA

9. Transgenics Section Laboratory of Neurogenetics National Institute on AgingNational Institutes of Health Bethesda MD USA

Funder

Guangdong Science and Technology Department

Guangzhou Municipal Science and Technology Project

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.202000017RR

Reference40 articles.

1. Clinical and pathological features of a parkinsonian syndrome in a family with an Ala53Thr ?-synuclein mutation

2. Genetics of Parkinson's disease and parkinsonism

3. Both Familial Parkinson's Disease Mutations Accelerate α-Synuclein Aggregation

4. Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

5. Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy

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2. Editorial: Novel mechanisms involved in aging and neurodegeneration: Seeking potential therapeutic targets for neurodegenerative diseases;Frontiers in Aging Neuroscience;2022-12-09

3. Tau Knockout and α-Synuclein A53T Synergy Modulated Parvalbumin-Positive Neurons Degeneration Staging in Substantia Nigra Pars Reticulata of Parkinson’s Disease-Liked Model;Frontiers in Aging Neuroscience;2022-01-11

4. Templated α-synuclein inclusion formation is independent of endogenous tau;eneuro;2021-05-10