A general strategy to inhibit serine protease by targeting its autolysis loop
Author:
Affiliation:
1. College of Chemistry Fuzhou University Fuzhou P.R. China
2. Fujian Key Laboratory of Marine Enzyme Engineering Fuzhou University Fuzhou P.R. China
3. College of Biological Science and Engineering Fuzhou University Fuzhou P.R. China
Funder
Natural Science Foundation of Fujian Province
National Natural Science Foundation of China
Publisher
Wiley
Subject
Genetics,Molecular Biology,Biochemistry,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.202002139RR
Reference63 articles.
1. Serine Protease Mechanism and Specificity
2. Strategies for the inhibition of serine proteases
3. Dissecting the catalytic triad of a serine protease
4. The catalytic triad of serine peptidases
5. Unique fold and active site in cytomegalovirus protease
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