Does metabolic radiolabeling stimulate the stress response? Gene expression profiling reveals differential cellular responses to internal beta vs. external gamma radiation

Author:

Marko Nicholas F.1,Dieffenbach Paul B.1,Yan Gai1,Ceryak Susan2,Howell Roger W.3,Mccaffrey Timothy A.1,Hu Valerie W.1

Affiliation:

1. Department of Biochemistry and Molecular Biology The George Washington University School of Medicine Washington, DC USA

2. Department of Pharmacology The George Washington University School of Medicine Washington, DC USA

3. Department of Radiology UMDNJ-New Jersey Medical School Newark New Jersey USA

Funder

National Science Foundation

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Reference43 articles.

1. DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.

2. p53 mediates permanent arrest over multiple cell cycles in response to γ-radiation;Linke S. P.;Cancer Res.,1997

3. CDC2 is down-regulated by ionizing radiation in a p53-dependent manner;Azzam E. I.;Cell Growth Differ.,1997

4. The Response of Proliferating Cell Nuclear Antigen to Ionizing Radiation in Human Lymphoblastoid Cell Lines Is Dependent on p53

5. Radiation-Induced Signal Transduction and Stress Response

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