Is Levoleucovorin an Alternative to Racemic Leucovorin? A Literature Review

Author:

Kovoor Philip A.,Karim Syed Mustafa,Marshall John L.

Publisher

Elsevier BV

Subject

Gastroenterology,Oncology

Reference26 articles.

1. Fluorouracil plus racemic leucovorin versus fluorouracil combined with the pure l-isomer of leucovorin for the treatment of advanced colorectal cancer: a randomized phase III study;Scheithauer;J Clin Oncol,1997

2. Lack of stereospecifity at carbon 6 of methyl-tetrahydrofolate transport in Ehrlich ascites tumor cells. Carrier-mediated transport of both stereoisomers;White;J Biol Chem,1978

3. Stereospecifity at carbon 6 of formyltetra-hydrofolate as a competitive inhibitor of transport and cytotoxicity of methotrexate in vitro;Sirotnak;Biochem Pharmacol,1979

4. Interaction of methotrexate and citrovorum factor at folylpolyglutamate synthetase;Sato;Proc Am Assoc Cancer Res,1984

5. Role of folylpolyglutamates in biochemical modulation of fluoropyrimidines by leucovorin;Romanini;Cancer Res,1991

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