Havanensin-type Limonoids from the Stem Bark of Chisocheton pentandrus (Meliaceae)
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Published:2023-05-15
Issue:3
Volume:54
Page:302-310
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ISSN:2338-5510
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Container-title:Journal of Mathematical and Fundamental Sciences
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language:
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Short-container-title:J. Math. Fund. Sci.
Author:
Runadi Dudi,Purnama Purnama,Salam Supriatno,Nurlelasari Nulelasari,Harneti Desi,Mayanti Tri,Maharani Rani,Supratman Unang,Shiono Yoshihito
Abstract
A new limonoid, belonging to the havanensin-type, called pentandricine E (1), alongside four other known types, i.e., trichilenone acetate (2), toonaciliatones C (3), 11α-acetoxyazadirone (4) and ceramicine I (5), were found in Chisocheton pentandrus stem bark. The structures of the isolated 1-5 were identified by NMR spectroscopy and HRTOFMS. Pentandricine E (1) displayed the highest cytotoxicity toward the MCF-7 breast cancer line with an IC50 value of 63.27 ± 0.21 mM.
Publisher
The Institute for Research and Community Services (LPPM) ITB
Subject
Multidisciplinary,General Physics and Astronomy,General Chemistry,General Biochemistry, Genetics and Molecular Biology,General Earth and Planetary Sciences,General Agricultural and Biological Sciences,General Mathematics,General Medicine
Cited by
2 articles.
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