The Three W's of Acetaminophen In Children: Who, Why, and Which Administration Mode?

Author:

Thibault Céline1234,Pelletier Élaine145,Nguyen Christina45,Trottier Evelyne D.46,Doré-Bergeron Marie-Joëlle34,DeKoven Kathryn47,Roy Anne-Marie48,Piché Nelson4,Delisle Jean-Francois45,Morin Caroline45,Paquette Julie48,Kleiber Niina1249

Affiliation:

1. Department of Pharmacology and Physiology (CT, NK), Université de Montreal, Montreal, QC, Canada

2. Research Center (CT, NK), CHU Sainte-Justine, Université de Montreal, Montreal, QC, Canada

3. Department of Pediatrics (CT, MJDB, NK), CHU Sainte-Justine, Montreal, QC, Canada

4. Groupe de Gouvernance des Analgésiques (CT, EP, CN, EDT, MJDB, KD, AMR, NP, JFD, CM, JP, NK), Pharmacology Committee, CHU Sainte-Justine, Montreal, QC, Canada

5. Department of Pharmacy (EP, CN, JFD, CM), CHU Sainte-Justine, Montreal, QC, Canada

6. Department of Pediatric Emergency Medicine (EDT), CHU Sainte Justine, Montreal, QC, Canada

7. Department of Anesthesiology (KD), CHU Sainte-Justine, Montreal, QC, Canada

8. Department of Nursing (AMR, JP), CHU Sainte-Justine, Montreal, QC, Canada

9. Department of Surgery (NP), CHU Sainte-Justine, Montreal, QC, Canada

Abstract

Acetaminophen is one of the oldest medications commonly administered in children. Its efficacy in treating fever and pain is well accepted among clinicians. However, the available evidence supporting the use of acetaminophen's different modes of administration remains relatively scarce and poorly known. This short report summarizes the available evidence and provides a framework to guide clinicians regarding a rational use of acetaminophen in children.

Publisher

Pediatric Pharmacy Advocacy Group

Subject

Pharmacology (medical),Pediatrics, Perinatology and Child Health

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3. Acute pain management in children: a survey of Italian pediatricians;Marseglia;Ital J Pediatr,2019

4. Pain in children--are we accomplishing the optimal pain treatment?;Lundeberg;Pediatr Anaesth,2015

5. Intravenous versus oral acetaminophen for pain: systematic review of current evidence to support clinical decision-making;Jibril;Can J Hosp Pharm,2015

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