Papillary Squamotransitional Cell Carcinoma Cervix: A Rare Variant

Abstract

ABSTRACT Papillary squamotransitional cell carcinoma (PSTCC) is a lesser known histological subtype of the most common type of cervical “squamous cell carcinoma (SCC).” Papillary carcinomas of the uterine cervix with transitional or squamous differentiation often resemble transitional cell carcinomas of the urinary tract. In the literature, PSTCC is underdiagnosed, has late presentation, is more common in postmenopausal age group, and has a late recurrence. Here we report a case of a 52-year-old lady presenting with postmenopausal bleeding, whose cytological evaluation reported atypical squamous cells of undetermined significance (ASCUS) and cervical biopsy as high-grade squamous intraepithelial lesion (HSIL). She underwent laparoscopic hysterectomy to be diagnosed with PSTCC mixed type. With an 18-month follow-up, she has shown no locoregional recurrence. A high index of suspicion on the part of the clinician and an awareness of PSTCC subtype of cancer cervix by the histopathologist are required to make an accurate diagnosis. How to cite this article Anant M, Singh A, Singh VY. Papillary Squamotransitional Cell Carcinoma Cervix: A Rare Variant. J South Asian Feder Menopause Soc 2017;5(2):142-144.