Orodental Local Drug Delivery

Abstract

ABSTRACT Oral mucosal diseases are the most common diseases affecting humans and these can be treated with the use of various drugs. These drugs can be administered via many routes to produce its pharmacological bioeffects. One such site is the oral cavity, where both local and systemic deliveries of drug can take place. Oral route has been the most convenient and commonly employed route of drug delivery. The oral mucosa's accessibility, excellent blood supply, bypass of hepatic first pass metabolism, rapid repair, and permeability profile make it an attractive site for local and systemic drug deliveries. Local drug delivery allows topical treatment of various oral mucosal diseases, as it provides a more targeted and efficient drug-delivery option than systemic delivery. This review highlights various methods of drug delivery and important aspects of mucoadhesive drug delivery and drug dosage for treatment of orodental diseases. How to cite this article Ahanthem N, Basavaraju SM, Pachipulusu B, Gazge N. Orodental Local Drug Delivery. J Health Sci Res 2015;6(2):41-46.