Localized Gingival Enlargement induced by Systemic Administration of Phenytoin for the Management of Epidermolysis Bullosa

Abstract

ABSTRACT Epidermolysis bullosa (EB) represents a spectrum of diseases that are characterized by increased fragility and blistering of the skin. At present, while there is no specific treatment for EB, the therapeutic approaches are essentially palliative, which aims at achieving an acceptable quality of life. A rare case of EB in a 15-year-old Indian boy who was on phenytoin for its proposed action on collagenase and who developed localized gingival overgrowth as a side effect is reported here. The patient presented with vesiculobullous lesion, anonychia, dental anomalies and high caries activity which are the clinical manifestations of EB. How to cite this article Gowda KS, Vinod S. Localized Gingival Enlargement induced by Systemic Administration of Phenytoin for the Management of Epidermolysis Bullosa. Int J Experiment Dent Sci 2015;4(1):58-61.