A Randomized Controlled Trial and Radiographic Evaluation of Adjunctive Periodontal Treatment with Calcium and Vitamin D Supplementation

Abstract

ABSTRACT Aim The objective of this study was to use clinical parameters, digital subtraction analysis, and computer intensity measurement to evaluate the effect of calcium and vitamin D supplementation in adult periodontitis patients with vertical bony defect after initial therapy. Materials and methods A total of 31 systemically healthy patients with moderate to severe chronic periodontitis and normal serum calcium level were included. The most obvious proximal vertical bony defect was selected in each patient as an area of interest (AOI). Subjects received initial periodontal therapy. They were randomized into two groups. The test group (n= 17) received calcium (600 mg twice daily) and vitamin D (0.25 µg once daily) supplements for 6 months. The control group (n= 14) received placebos. At baseline and 6 months, probing pocket depth (PPD), clinical attachment level (CAL), and standardized vertical bitewing radiographs were recorded for the AOI. Results A greater percentage of patients in the test group (64.7%) than in the control group (35.7%) gained bone according to both radiographic evaluation methods. At baseline and 6 months, no significant intragroup or intergroup differences in PPD and CAL were observed. Slightly greater PPD reduction and CAL gain were noted in the test group. Conclusion Periodontal healing of vertical bony defects was better among patients who used calcium and vitamin D supplements than among control patients. Although the difference was not statistically different between the groups, the test group tended toward more improvement. How to cite this article Bundit A, Yotnuengnit P, Wisetsin S, Chittacharoen A. A Randomized Controlled Trial and Radiographic Evaluation of Adjunctive Periodontal Treatment with Calcium and Vitamin D Supplementation. Int J Experiment Dent Sci 2016;5(1):50-55.