Calciphylaxis in Renal Hyperparathyroidism: A Case-based Review

Abstract

ABSTRACT Calciphylaxis is a rare fatal condition associated with chronic renal failure, with a prevalence of about 4%. The condition is associated with microcalcification of small- and medium-sized arteries, leading to skin ischemia, necrosis, and gangrene. Any part of the body may be involved, but it is predominant in the lower extremities. Severe pain is usually associated with ulcers and may be difficult to manage. Although parathyroidectomy may improve the symptoms, the prognosis remains dismal with a high mortality. We present a case of severe calciphylaxis associated with renal hyperparathyroidism and briefly review the literature on the condition. How to cite this article Tan S, Yuan NK, Lim DGZ, Parameswaran R. Calciphylaxis in Renal Hyperparathyroidism: A Case-based Review. World J Endoc Surg 2016;8(2):156-159.