Central Giant Cell Granuloma of the Jaws: A Short Series and Review of Literature

Abstract

ABSTRACT Introduction Central giant cell granuloma (CGCG) accounts for less than 7% of all lesions of the jaw. It occurs more commonly in the anterior mandible compared to the maxilla. Females have 2 to 3 times higher incidence. Children and young adults are affected the most. Materials and methods The present series reviews 10 cases of CGCG suspected on clinical and radiologic basis and confirmed by histopathologic examination. Results The age of 10 cases ranged from 7 to 32 years (mean age 19.8); there were six females and four males; six had lesion in the lower jaw and the remaining four in the upper jaw. After radiologic evaluation, the treatment involved surgical curettage which was subjected to histopathologic examination and diagnosed as CGCG. Conclusions CGCG is diagnosed by a combination of clinical and radiologic findings and confirmed by histopathology. The condition needs to be distinguished from other giant cell containing lesions. The early and precise diagnosis of CGCG allows conservative management with minimal risk to the adjacent tooth or bone.