Postmyomectomy Reproductive Outcome in Women above 35 years

Abstract

ABSTRACTThe aim of this retrospective study was to assess the conception rate, reproductive outcome and complications after myomectomy in women aged above 35 years. Myomectomy was performed using abdominal and laparoscopic technique.Myomectomy was performed in 50 women in this study. By abdominal method in 35 cases (75%) and laparoscopic-assisted method in 15 cases (30%). Overall conception rate is 20% which occurred after one to one and half year postmyomectomy. Multiple regression analysis showed that age was the only factor which influenced the conception rate: < 35 years, 70% (21/30); > 35 years, 20% (10/50; p < 0.005). Risks for spontaneous abortions (8%), pre-eclampsia (10%), preterm labor (4%) and gestational diabetes (10%) are increased.All cases were delivered by cesarean section. No case of uterine rupture is seen. The retrospective study suggests that myomectomy after 35 years has only a slight increase in the reproductive performance in women presenting with infertility and has a higher risk for preeclampsia, gestational diabetes, preterm labor and NICU admission of the newborns.