Polymyositis

Abstract

ABSTRACT Polymyositis is an uncommon inflammatory disease that causes muscle weakness affecting both sides of the body, typically the proximal muscles. Most commonly, it affects adults in their 30s, 40s, or 50s. Signs and symptoms usually develop gradually, over weeks or months. Raised creatinine phosphokinase (CPK) levels are commonly seen during the acute phase. The electromyogram characteristically shows a myopathic pattern. The affected muscles histopathologically demonstrate endomysial inflammation, lymphocytic infiltration, zonalmyofibrillar loss, and perifascicular atrophy. We report a male patient with a classical presentation of polymyositis. How to cite this article Cheema YS, Gupta P, Attri S, Jamdagni V, Mittal D. Polymyositis. J Postgrad Med Edu Res 2016;50(4):199-200.