Adipokines/cytokines and disturbances in lipid metabolism

Author:

Spiridonov A. N.1ORCID,Khudiakova A. D.1ORCID,Ragino Yu. I.1ORCID

Affiliation:

1. Research Institute of Internal and Preventive Medicine – Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences

Abstract

This review presents the results of investigations in the field of studying the association of adipokines secreted by visceral adipocytes and the level of low-density lipoprotein cholesterol. In relation to this association, such adipokines as adiponectin, plasminogen activator inhibitor 1 (PAI-1), resistin, interleukin 1 beta (IL-1β), monocyte-chemoattractant protein type 1 (MCP-1), nerve growth factor (NGF), visfatin, omentin-1, and the pancreatic hormone insulin were analyzed. The results of studies that have studied the pathogenetic (in animal models) and clinical role of this association in humans are presented. Information on the topic from the publications of the PubMed, Google Scholar databases was used. 

Publisher

The Institute of Internal and Preventive Medicine

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