Formulation of an Ointment from Hydroethanolic Extract of Terminalia ivorensis and Therapeutic Trial on Volunteers with Moths

Author:

Sitapha Ouattara1,Constance Désirée Ruth N’guessan1,Issa Bagré1,Kouassi Elisée Kporou2,Adou Koffi Mathieu Kra1,Allico Joseph Djaman3

Affiliation:

1. Biology and health Laboratory, Department of Biosciences, Félix Houphouët Boigny, Cocody (Abidjan), Ivory Coast.

2. Biochemistry-Microbiology laboratory, BIONAS Team, University Jean Lorougnon Guédé, Daloa, Ivory Coast.

3. Department of Clinical and fundamental biochemistry, Pasteur Institute, Abidjan, Ivory Coast

Abstract

This study was conducted to make a contribution in the treatment of dermatosis, particularly moths. Ointments of different concentrations made from the hydroethanolic extract of Terminalia ivorensis and shea butter were used. The best results were obtained with the following concentrations: C4: 0.01 g/mL; C5: 0.0125 g/mL; C6: 0.015 g/mL and C10: 0.025 g/mL for trichophytic clipping moth on eleven (11) selected persons with ringworm and C9: 0.0225 g/mL for microsporic clipping moth on one (1) person. The present study really provides the scientific basis for the use of this plant in the traditional treatment of diseases and may help to discover new chemical classes of antifungal substances that could serve as selective agents for infectious disease chemotherapy.

Publisher

JACS Directory

Reference21 articles.

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5. L.F. Biyiti, V. Tamze, N. Nnanga, A.G. Agbor, J. Gangoue-pieboji, Formulation of an antibacterial ointment based on an ethanolic extract of the bark of Tabernaemontana crassa Benth trunk, Eur. Sci. J. 10 (2012) 87-95.

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