Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression-Reference-Cited by-同舟云学术

Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression

Published:2009 Issue:10 Volume:41 Page:717
ISSN:1226-3613
Container-title:Experimental and Molecular Medicine
language:en
Short-container-title:Exp Mol Med

Author:

Wang Zhipeng¹,Jin Haifeng²,Xu Ruodan³,Mei Qibing¹,Fan Daiming²

Affiliation:

1. Department of Pharmacology, School of Pharmacy, Xijing Hospital, The Fourth Military Medical University, Shaanxi Province 710032, China.

2. State Key Laboratory of Cancer Biology and Institute of Digestive Diseases, Xijing Hospital, The Fourth Military Medical University, Shaanxi Province 710032, China.

3. Protein Laboratory, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen 2200, Denmark.

Publisher

Springer Science and Business Media LLC

Subject

Clinical Biochemistry,Molecular Biology,Molecular Medicine,Biochemistry

Reference30 articles.

1. Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

2. Involvement of IL-6 in the Pathogenesis of Inflammatory Bowel Disease and Colon Cancer

3. Signaling Molecules: The Pathogenic Role of the IL-6/STAT-3 Trans Signaling Pathway in Intestinal Inflammation and in Colonic Cancer

4. Interleukin-6 Blood Level Is Associated With Circulating Carcinoembryonic Antigen and Prognosis in Patients With Colorectal Cancer

5. Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)

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