Conversion of a murine monoclonal antibody A13 targeting epidermal growth factor receptor to a human monoclonal antibody by guided selection
Author:
Affiliation:
1. Antibody Engineering Lab, Central Research Center, Green Cross Corp., Yongin 446-770, Korea.
Publisher
Springer Science and Business Media LLC
Subject
Clinical Biochemistry,Molecular Biology,Molecular Medicine,Biochemistry
Reference28 articles.
1. Isolating human antibody against human hepatocellular carcinoma by guided-selection
2. Phase I Safety, Pharmacokinetic, and Pharmacodynamic Trial of ZD1839, a Selective Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Five Selected Solid Tumor Types
3. Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent
4. Anti-epidermal growth factor receptor monoclonal antibodies in cancer treatment
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