Preclinical studies for pharmacokinetics and biodistribution of Ad-stTRAIL, an adenovirus delivering secretable trimeric TRAIL for gene therapy

Author:

Kim Chae-Young12,Park Soon-Hye1,Jeong Moonsup1,Kwon O-Seo1,Doh Hyounmie1,Kang Su-Hyung1,Robbins Paul D.3,Kim Byong-Moon1,Seol Dai-Wu45,Kim Byung-Gee2

Affiliation:

1. Biopharmaceutical Research Laboratories of Dong-A Pharmaceutical Co., Ltd., Kyunggi-Do 446-905, Korea.

2. Interdisciplinary Program of Biochemical Engineering and Biotechnology, Seoul National University, Seoul 151-744, Korea.

3. Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pennsylvania PA15261, USA.

4. Faculty of Pharmacy, College of Pharmacy, Chung-Ang University, Seoul 156-756, Korea.

5. Department of Surgery, University of Pittsburgh School of Medicine, Pennsylvania PA15261, USA.

Publisher

Springer Science and Business Media LLC

Subject

Clinical Biochemistry,Molecular Biology,Molecular Medicine,Biochemistry

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