Synthesis of poly(D,L-lactide) with controlled molecular weight and type of end-groups

Author:

Atamanova A. A.1,Spirin O. A.2,Sedush N. G.1

Affiliation:

1. Enikolopov Institute of Synthetic Polymeric Materials RAS; National Research Center «Kurchatov Institute»

2. Petrovsky National Research Centre of Surgery

Abstract

   The synthesis of poly(D,L-lactide) with a predetermined molecular weight ranging from 5 to 143 kDa was conducted by ringopening polymerization of lactide in the presence of varying concentrations of the 1,12-dodecanediol activator. To synthesize poly(D,L-lactide) with COOH-end groups, polymerization was carried out in the presence of L-lactic acid. The synthesised polymer was found to contain an order of magnitude higher concentration of COOH groups than poly(D,L-lactide) synthesised in the presence of 1,12-dodecanediol.

Publisher

Publishing House Plastic Ltd

Subject

Polymers and Plastics,Chemical Engineering (miscellaneous)

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