Affiliation:
1. Internal Medicine Residency Spokane
2. University of Washington
3. Washington State University
Abstract
A previously healthy 69-year-old female admitted to the hospital with refractory hypotension fevers and diarrhea. She had two prior hospitalizations with similar presentations and no clear etiology could be identified. During her current hospitalization, she was admitted to the intensive care unit (ICU) due to refractory shock. Despite an extensive work up with multiple subspecialty consultation, the patient ultimately transitioned to comfort care. Autopsy report revealed extensive large b-cell lymphocyte involvement within the vasculature of the majority of her organs. This case of intravascular large B-cell lymphoma (ILBCL) exemplifies the necessity to include it on a broadened differential when shock becomes refractory.
Publisher
Department of Medicine, Warren Alpert Medical School at Brown University
Reference11 articles.
1. Challenges and opportunities in primary CNS lymphoma: A systematic review;Mariana N. Kerbauy;Radiotherapy and Oncology,2017
2. DA-R-EPOCH vs R-CHOP in DLBCL: How do we choose?;A. Major;Clin Adv Hematol Oncol,2021
3. An Asian variant of intravascular large B-cell lymphoma: clinical, pathological and cytogenetic approaches to diffuse large B-cell lymphoma associated with haemophagocytic syndrome;T. Murase;Br J Haematol,2000
4. Retrospective study of intravascular large B-cell lymphoma cases diagnosed in Quebec: A retrospective study of 29 case reports;Vanessa Brunet;Medicine,2017
5. Intravascular lymphoma: clinical presentation, natural history, management and prognostic factors in a series of 38 cases, with special emphasis on the 'cutaneous variant';A.J. Ferreri;Br J Haematol,2004