1. Laboratory of Electrophysiology and Cardiovascular Pharmacology, Faculty of Health Sciences, Federal University of Grande Dourados (UFGD), Dourados, MS, Brazil.
2. Laboratory of Preclinical Research of Natural Products, Paranaense University (UNIPAR), Umuarama, Parana´, Brazil.
3. Institute of Research Pelé Pequeno Príncipe, Pequeno Príncipe Faculty, Curitiba, Paraná, Brazil.