HIV-1 Full-Genome Phylogenetics of Generalized Epidemics in Sub-Saharan Africa: Impact of Missing Nucleotide Characters in Next-Generation Sequences

Author:

Ratmann Oliver1,Wymant Chris2,Colijn Caroline3,Danaviah Siva4,Essex Max56,Frost Simon7,Gall Astrid7,Gaseitsiwe Simani6,Grabowski Mary K.89,Gray Ronald89,Guindon Stephane1011,von Haeseler Arndt1213,Kaleebu Pontiano14,Kendall Michelle3,Kozlov Alexey15,Manasa Justen4,Minh Bui Quang12,Moyo Sikhulile6,Novitsky Vlad56,Nsubuga Rebecca14,Pillay Sureshnee4,Quinn Thomas C.91617,Serwadda David918,Ssemwanga Deogratius14,Stamatakis Alexandros1519,Trifinopoulos Jana12,Wawer Maria89,Brown Andy Leigh20,de Oliveira Tulio21,Kellam Paul22,Pillay Deenan423,Fraser Christophe2,on behalf of the PANGEA-HIV Consort

Affiliation:

1. MRC Centre for Outbreak Analyses and Modelling, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom.

2. Oxford Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

3. Department of Mathematics, Imperial College London, London, United Kingdom.

4. Africa Health Research Institute, KwaZulu-Natal, South Africa.

5. Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

6. Botswana Harvard AIDS Institute Partnership, Gaborone, Botswana.

7. Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.

8. Department of Epidemiology Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

9. Rakai Health Sciences Program, Entebbe, Uganda.

10. Department of Statistics, University of Auckland, Auckland, New Zealand.

11. Laboratoire d'Informatique, de Robotique et de Microelectronique de Montpellier–UMR 5506, CNRS & UM, Montpellier, France.

12. Centre for Integrative Bioinformatics Vienna, Max F. Perutz Laboratories, University of Vienna, Medical University of Vienna, Vienna, Austria.

13. Bioinformatics and Computational Biology, Faculty of Computer Science, University of Vienna, Vienna, Austria.

14. MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda.

15. Heidelberg Institute for Theoretical Studies, Heidelberg, Germany.

16. Division of Intramural Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland.

17. Department of Medicine Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

18. Makerere University School of Public Health, Makerere University College of Health Sciences, Kampala, Uganda.

19. Institute for Theoretical Informatics, Karlsruhe Institute of Technology, Karlsruhe, Germany.

20. School of Biological Sciences, Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom.

21. Nelson R. Mandela School of Medicine, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

22. Department of Infectious Diseases and Immunity, Imperial College London, United Kingdom.

23. Division of Infection & Immunity, Faculty of Medical Sciences, University College London, London, United Kingdom.

Publisher

Mary Ann Liebert Inc

Subject

Infectious Diseases,Virology,Immunology

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