Developing a Gene Therapy for the Treatment of Autosomal Dominant Alzheimer's Disease-Reference-Cited by-同舟云学术

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Developing a Gene Therapy for the Treatment of Autosomal Dominant Alzheimer's Disease

Published:2023-10-01 Issue:19-20 Volume:34 Page:1049-1063
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Moore Benjamin¹,Sharma Apurwa¹,Goulet Martin¹,Suter Tracey¹^ORCID,Pelletier Carolyn¹,Hu Ruoxi¹²,Schaeffer Eric¹^ORCID,Kelleher Raymond J.³⁴

Affiliation:

1. Paros Bio, Boston, Massachusetts, USA.

2. Mass General Brigham Ventures (Partners Innovation Fund), Boston, Massachusetts, USA.

3. Department of Neurology, and Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.

4. Program in Neuroscience, Harvard Medical School, Boston, Massachusetts, USA.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

https://www.liebertpub.com/doi/pdf/10.1089/hum.2023.092

Reference29 articles.

1. Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

2. Genetic Heterogeneity in Alzheimer Disease and Implications for Treatment Strategies

3. The presenilin hypothesis of Alzheimer's disease: Evidence for a loss-of-function pathogenic mechanism

4. A Presenilin-1 Mutation Identified in Familial Alzheimer Disease with Cotton Wool Plaques Causes a Nearly Complete Loss of γ-Secretase Activity

5. Trans-Dominant Negative Effects of Pathogenic PSEN1 Mutations on -Secretase Activity and A Production

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Gene therapy for CNS disorders: modalities, delivery and translational challenges;Nature Reviews Neuroscience;2024-06-19

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