Optimization Approaches for the In Silico Discovery of Optimal Targets for Gene Over/Underexpression
Author:
Affiliation:
1. Department of Informatics/CCTC, University of Minho, Braga, Portugal.
2. IBB-Institute for Biotechnology and Bioengineering/Centre of Biological Engineering, Universidade do Minho, Braga, Portugal.
Publisher
Mary Ann Liebert Inc
Subject
Computational Theory and Mathematics,Computational Mathematics,Genetics,Molecular Biology,Modelling and Simulation
Link
http://www.liebertpub.com/doi/pdf/10.1089/cmb.2011.0265
Reference13 articles.
1. Optknock: A bilevel programming framework for identifying gene knockout strategies for microbial strain optimization
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3. Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth
4. Evolutionary programming as a platform for in silico metabolic engineering
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