HER2-Mediated Internalization of a Targeted Prodrug Cytotoxic Conjugate Is Dependent on the Valency of the Targeting Ligand-Reference-Cited by-同舟云学术

HER2-Mediated Internalization of a Targeted Prodrug Cytotoxic Conjugate Is Dependent on the Valency of the Targeting Ligand

Published:2005-06 Issue:6 Volume:24 Page:351-358
ISSN:1044-5498
Container-title:DNA and Cell Biology
language:en
Short-container-title:DNA and Cell Biology

Author:

Guillemard Veronique¹,Nedev Hinyu N.¹,Berezov Alan²,Murali Ramachandran²,Saragovi H. Uri¹

Affiliation:

1. McGill University, Pharmacology and Therapeutics and Oncology/Cancer Center, Lady Davis Research Institute–Jewish General Hospital, Montreal, Quebec, Canada.

2. Department of Pathology and Laboratory Medicine, Abramson Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Genetics,Molecular Biology,General Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/dna.2005.24.351

Reference39 articles.

1. Selective Cleavage of the Heregulin Receptor ErbB-4 by Protein Kinase C Activation

2. Disabling ErbB Receptors with Rationally Designed Exocyclic Mimetics of Antibodies: Structure−Function Analysis

3. Disabling Receptor Ensembles with Rationally Designed Interface Peptidomimetics

4. Structure of antibody hypervariable loops reproduced by a conformational search algorithm

5. The Retro-inverso Form of a Homeobox-Derived Short Peptide Is Rapidly Internalized by Cultured Neurons: A New Basis for an Efficient Intracellular Delivery System

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