Intracerebral and Intrathecal Infusion of the TGF-β2-Specific Antisense Phosphorothioate Oligonucleotide AP 12009 in Rabbits and Primates: Toxicology and Safety
Author:
Affiliation:
1. Antisense Pharma GmbH, 93053 Regensburg, Germany.
2. Klinik und Poliklinik für Neurologie der Universität Regensburg, 93053 Regensburg, Germany.
3. Neurochirurgie an der Lohengrin Therme, 95448 Bayreuth, Germany.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/oli.2005.15.94
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1. Distribution and stability of antisense phosphorothioate oligonucleotides in rodent brain following direct intraparenchymal controlled-rate infusion
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3. The application of antisense oligonucleotide technology to the brain: Some pitfalls
4. Transforming Growth Factor-Beta: Antisense RNA-Mediated Inhibition Affects Anchorage-Independent Growth, Tumorigenicity and Tumor-Infiltrating T-Cells in Malignant Mesothelioma
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