Development of a QPatch-Automated Electrophysiology Assay for Identifying TMEM16A Small-Molecule Inhibitors
Author:
Affiliation:
1. Department of Process Development, Amgen, Inc., Thousand Oaks, California, USA.
2. Department of Inflammation Discovery Research, Amgen, Inc., Thousand Oaks, California, USA.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Molecular Medicine
Link
https://www.liebertpub.com/doi/pdf/10.1089/adt.2019.962
Reference41 articles.
1. TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity
2. Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit
3. TMEM16A confers receptor-activated calcium-dependent chloride conductance
4. Chloride Channels - New Targets for the Prevention of Stroke
5. Studies on expression and function of the TMEM16A calcium-activated chloride channel
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2. The Tmem16a chloride channel is required for mucin maturation after secretion from goblet-like cells in the Xenopus tropicalis tadpole skin.;2024-04-16
3. Niclosamide potentiates TMEM16A and induces vasoconstriction;2023-08-02
4. Emerging Modulators of TMEM16A and Their Therapeutic Potential;The Journal of Membrane Biology;2021-07-14
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