Impact of AAV Capsid-Specific T-Cell Responses on Design and Outcome of Clinical Gene Transfer Trials with Recombinant Adeno-Associated Viral Vectors: An Evolving Controversy
Author:
Affiliation:
1. Wistar Institute, Philadelphia, Pennsylvania.
2. Spark Therapeutics, Philadelphia, Pennsylvania.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hum.2016.172
Reference99 articles.
1. Gene therapy for the hemophilias
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3. Recombinant adeno-associated virus for muscle directed gene therapy
4. Long-term correction of inhibitor-prone hemophilia B dogs treated with liver-directed AAV2-mediated factor IX gene therapy
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